Big Three is the nickname with which the group of three tennis players made up of Novak Djokovic, Roger Federer and Rafael Nadal is identified.

From the 2003 Australian Open to the 2023 Australian Open, the trio dominated the men's singles circuit by winning 64 of 79 (81%) Grand Slam titles, also reaching 94 finals during this span. Djokovic and Nadal hold the all-time record for total titles won with 22 Grand Slams, followed by Federer with 20. Overall, they have won 18 Australian Opens, 17 Roland Garros, 17 Wimbledon and 12 US Opens.

The three have won 18 consecutive Grand Slams from 2005 Roland Garros to Wimbledon in 2009, 11 consecutive Grand Slams from 2010 Australian Open to 2012 Wimbledon, and 13 in a row from 2017 Australian Open to 2020 Australian Open.

One of the Big Three is was the ATP No. 1 year-end every year from 2004 to 2021 except 2016 (17 of the last 18 years). Together, they have occupied the top three positions in the ATP singles rankings at the end of the year eight times, in 2007, 2008, 2009, 2010, 2011, 2014, 2018 and 2019.

Federer, Nadal and Djokovic have completed the Career Grand Slam by winning all four tournaments at least once in their careers. Nadal also won a gold medal at the 2008 Summer Olympics by completing the Career Golden Slam, and both Nadal and Djokovic have won every Grand Slam tournament at least twice (the former having won the Australian Open in 2022 and the second with Roland Garros victory in 2021).

The Big Three hold the record for victories in the four Slams, (Djokovic with 10 in the Australian Open, Nadal with 14 in Roland Garros, Federer with 8 at Wimbledon); the ATP Finals, the Masters 1000, and the ATP 500 in general.